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Is Sodium hyaluronate injection the most useful solution for knee osteoarthritis?
2021-01-06 14:50:23112

Sodium hyaluronate injection,the most useful solution for knee osteoarthritis?

There are many ways to treat knee osteoarthritis in clinic, including conservative treatment and surgical treatment. Sodium Hyaluronate (SH) injection into the joint cavity is a more commonly used conservative treatment method.

If you suffer from Knee joint pain, some people may suggest to inject sodium hyaluronate into the joint, so today we are going to talk about whether this sodium hyaluronate is useful? What is sodium hyaluronate? 

What is sodium hyaluronate?

Sodium hyaluronate, also known as sodium hyaluronate, is a kind of high molecular polysaccharide biomaterial formed by N-acetylglucuronic acid. Hyaluronic acid molecules can carry more than 500 times more water. It is an ideal natural moisturizing factor, distributed in human skin, joint synovial fluid and eye vitreous.

What can sodium hyaluronate do in human body?

The unique molecular structure and physical and chemical properties of sodium hyaluronate show a variety of important physiological functions in the human body, such as lubricating joints, regulating the permeability of blood vessel walls, regulating proteins, and promoting wound healing.(ps.The main component of synovial fluid secreted in the knee joint cavity is sodium hyaluronate.)

The synovial fluid filled in the knee joint plays a role in lubricating and absorbing shocks during the repeated flexion and extension movement and friction of the knee joint. Because of the presence of sodium hyaluronate in synovial fluid, it can reduce the impact on the bones of the human body during walking and sports, and secondly, it can also reduce the friction between tissues. Therefore, normal synovial fluid is essential for the daily activities of the knee joint.

What is the use of sodium hyaluronate injection?

The role of sodium hyaluronate injection is often known as a lubricant, and its main component is sodium hyaluronate.

In the synovial fluid of knee joint injuries, the output and quality of its own sodium hyaluronate will decrease, so the friction loss of the joint will be more and the pain will also be plentiful.

When sodium hyaluronate injection is injected into the joint cavity, it will increase the content of sodium hyaluronate in the joint synovial fluid, thereby improving the inflammatory response of the synovial fluid tissue, reducing the friction between the tissues, and enhancing the viscosity and lubricating function of the joint fluid , Protect articular cartilage, increase joint mobility and relieve pain.

ha injection for osteoarthritis


Who are applicable people of sodium hyaluronate injection?


Under normal circumstances, joint synovial fluid decreases with age, so for middle-aged and elderly people, their degenerative changes reduce the secretion of synovial fluid in the joint itself and cause joint pain. This requires injection of hyaluronic acid sodium.

Therefore, sodium hyaluronate injection is clinically suitable for mild to moderate degenerative osteoarthritis.

Precautions and risks of sodium hyaluronate injection:

1.Joint injections cannot be done for local skin infections or joint mobility infections. This is an absolute contraindication. 

2.Because it is intra-articular injection, strict aseptic operation must be performed during injection. 

3.Injection of sodium hyaluronate will have side effects, such as pain at the injection site, joint stiffness, short-term swelling, etc. Generally, cold compress, rest or take some non-steroidal anti-inflammatory drugs can alleviate it. 

4.Avoid excessive weight bearing on the injected knee joint, avoid running or standing for a long time within a few days after injection.